Unlocking mammalian regeneration through hypoxia inducible factor one alpha signaling
نویسندگان
چکیده
منابع مشابه
Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha
Histone deacetylase inhibitors (HDACis) are a potent class of tumor-suppressive agents traditionally believed to exert their effects through loosening tightly-wound chromatin resulting in de-inhibition of various tumor suppressive genes. Recent literature however has shown altered intratumoral hypoxia signaling with HDACi administration not attributable to changes in chromatin structure. We sou...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2021
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2020.120646